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December 8, 2025Blood

Real-world stratified treatment strategies in transplant-eligible newly diagnosed multiple myeloma: A multicohort study

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Authors

LKLifen KuangJLJuan Li

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Overview

Multicohort analysis shows improved progression-free survival in transplant-eligible multiple myeloma based on risk profiles and therapies.

Key Points

  • Mobilization success was achieved in every cohort indicating robust treatment approaches.
  • The ultrahigh-risk group achieved a median progression-free survival of 25 months with daratumumab-based therapy.
  • Complete response rates were high in both ultrahigh-risk and extramedullary cohorts, highlighting treatment efficacy.
  • Risk-adapted strategies support better outcomes across diverse multiple myeloma patient profiles.

Cite This Study

Kuang et al. (2025) studied this question.

synapsesocial.com/papers/69362f5d4fa91c937236dbf6https://doi.org/10.1182/blood-2025-7541
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