Analysis reveals whole brain radiotherapy improves overall survivorship in primary central nervous system lymphoma, suggesting potential safety in elderly patients.
Key Points
Overall survival was improved with whole brain radiotherapy used as consolidation after chemotherapy, and was particularly effective in achieving complete remission.
Progression-free survival rates indicate a strong positive response to the treatment, with 72.58% of patients achieving complete remission post-therapy.
Assessment through minimum mental state examination highlighted preserved cognition, with no significant cognitive impairment detected after whole brain radiotherapy.
Results suggest that low-dose whole brain radiotherapy is feasible for older patients, emphasizing the need for prospective trials to assess neurocognitive outcomes for various treatments.