Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025BloodOpen Access

Safety and efficacy of zanubrutinib in waldenstrom macroglobulinemia patients treated in common clinical practice: A retrospective-prospective study by fondazione italiana linfomi (FIL)

View Full Paper
Ask AI
Bookmark
Share

Authors

FAFrancesco AutoreFPFrancesco PiazzaGDGiulia Daghia

Discussion

Loading...

Member takes

Overview

Retrospective-prospective study shows safety and effectiveness of zanubrutinib in waldenström macroglobulinemia patients, highlighting adverse events and treatment outcomes.

Key Points

  • Over 89% of patients remained on zanubrutinib treatment after 12 months, indicating safety and adherence.
  • The overall response rate was 89.7%, with a progression-free survival of 92% after treatment with zanubrutinib.
  • Retrospective-prospective study evaluated treatment management, safety, and outcomes in waldenström macroglobulinemia patients.
  • The findings suggest zanubrutinib has a favorable safety profile in a cohort with substantial comorbidities and age factors.

Cite This Study

Autore et al. (2025) studied this question.

synapsesocial.com/papers/69362f5a4fa91c937236db2ahttps://doi.org/10.1182/blood-2025-5360
View Full Paper
Ask AI
Bookmark
Share