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December 8, 2025Blood

Patient outcomes for sickle cell disease with support staff-driven interventions: A scoping review

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Authors

SGShenise GilyardAPAmie Patel

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Overview

Scoping review reports limited benefit of support staff interventions on healthcare utilization in sickle cell disease, highlighting need for integrated care models.

Key Points

  • Healthcare utilization did not significantly improve from support staff interventions in sickle cell disease.
  • Six of nine included studies were randomized controlled trials or observational studies, mainly in pediatric populations.
  • Support staff roles like community health workers can aid healthcare utilization but show mixed results on medication adherence.
  • Future randomized controlled trials are needed to explore care coordination outcomes related to chronic care models.

Cite This Study

Gilyard et al. (2025) studied this question.

synapsesocial.com/papers/69362f514fa91c937236d942https://doi.org/10.1182/blood-2025-7892
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Implementation of a comprehensive sickle cell center leads to improved access to care and decreased acute care use2026
  2. 2The role of palliative care in sickle cell disease: A single database literature review of contemporary outcomes data2025
  3. 3Consolidation of adult inpatient sickle cell care to improve patients' and learners' experiences: A qualitative exploration of various stakeholders' perspectives2025
  4. 4Implementing linkage coordination: Patient experiences in the recruitment and engagement in care to impact practice enhancement (RECIPE) for sickle cell disease study2025
  5. 5Improvement of sickle cell disease care mitigates the healthcare utilization induced by increased prevalence: Experience of a tertiary pediatric center2025