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December 8, 2025Parasitology ResearchOpen Access

Effect of antiserum against recombinant EGr₀9888 on the in vitro development of Echinococcus granulosus protoscoleces

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Authors

WKWulijiang KamaliWBWan-Li BanYMYongping Mu

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Overview

Immunofluorescence staining revealed diminished gene expression and survival rate in Echinococcus granulosus protoscoleces after anti-EGr_09888 treatment, suggesting vaccine potential.

Key Points

  • Survival rate of Echinococcus granulosus protoscoleces significantly decreased with rabbit anti-EGr_09888 serum treatment.
  • Gene expression analysis demonstrated that EGr_09888 is a candidate for vaccine development.
  • Immunofluorescence staining localized EGr_09888 predominantly in adult worm segments, reinforcing its potential role.
  • B- and T-cell epitopes identified in EGr_09888 indicate its immunogenic potential for future vaccine applications.

Cite This Study

Kamali et al. (2025) studied this question.

synapsesocial.com/papers/69362f4e4fa91c937236d89dhttps://doi.org/10.1007/s00436-025-08604-y
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