Chronological age predicts suboptimal multiple myeloma treatment independent of frailty and socioenvironmental factors: A retrospective multi-center cohort study
Retrospective analysis identifies age as a key factor affecting treatment outcomes in multiple myeloma, suggesting potential for improvement in care strategies.
Key Points
Increasing chronological age predicts lower optimal treatment rates in multiple myeloma patients, underscoring age-related disparities.
Among 4,887 patients from the VA, 71.9% received optimal treatment, with age correlating negatively with therapy success rates.
This observational analysis utilized the Veterans Affairs Frailty Index to assess treatment patterns linked to age and comorbidities.
Future approaches in multiple myeloma treatment may need to integrate frailty assessments to enhance precision medicine and equitable care.