December 8, 2025BloodOpen Access

Infection risk factors and burden in patients treated with T-cell engaging bispecific antibodies for relapsed B-cell lymphoma and multiple myeloma

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Observational analysis reveals high infection rates in relapsed B-cell lymphoma and multiple myeloma, indicating a need for tailored prophylaxis.

113 patients had infections during treatment, with 66% of events being bacterial.
Key findings included 28% of patients with NHL and 72% with multiple myeloma showing significant risks for infections.
Analysis using Wilcoxon rank sum test identified baseline levels of albumin as a risk factor for infections.
Findings suggest IVIG could mitigate severe infection rates, highlighting the importance of personalized patient management.

Mian et al. (2025) studied this question.

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December 8, 2025BloodOpen Access

View Full Paper

Ask AI

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Authors

Observational analysis reveals high infection rates in relapsed B-cell lymphoma and multiple myeloma, indicating a need for tailored prophylaxis.

113 patients had infections during treatment, with 66% of events being bacterial.
Key findings included 28% of patients with NHL and 72% with multiple myeloma showing significant risks for infections.
Analysis using Wilcoxon rank sum test identified baseline levels of albumin as a risk factor for infections.
Findings suggest IVIG could mitigate severe infection rates, highlighting the importance of personalized patient management.

Mian et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark