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December 8, 2025Blood

Continued risk of relapse in peripheral T-cell lymphoma even in patients who achieved complete response after initial therapy

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Authors

YSYuko ShirouchiYMYuka MoritaDMDai Maruyama

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Overview

Retrospective analysis reveals high relapse rates in patients with peripheral T-cell lymphoma, suggesting need for improved treatment strategies.

Key Points

  • Over half of patients achieving complete response relapsed, highlighting ongoing risks after therapy.
  • The median progression-free survival for those relapsing was notably low at 9 months post-relapse.
  • Patients receiving Brentuximab vedotin as salvage therapy showed better post-relapse outcomes compared to conventional methods.
  • Long-term monitoring is crucial, as initial response duration did not significantly impact subsequent survival rates.

Cite This Study

Shirouchi et al. (2025) studied this question.

synapsesocial.com/papers/69362f484fa91c937236d73ahttps://doi.org/10.1182/blood-2025-7152
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