December 8, 2025BloodOpen Access

Addressing functional asplenia in sickle cell disease: A quality improvement approach to improve vaccination rates

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Authors

EKEvan KeiserUniversity of Wisconsin–Madison

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Implication

Quality improvement initiatives improved pneumococcal and influenza vaccination rates in adults with sickle cell disease, suggesting better adherence strategies are needed.

Key Points

Vaccination rates improved to 41.7% for pneumococcal and 27.8% for influenza, showing initial efficacy of structured interventions.
An interdisciplinary team developed a workflow for patient education and vaccination adherence, addressing significant care gaps.
Root cause analysis identified barriers to vaccination rates, leading to improvements in clinical practice.
Continued assessment through PDSA cycles will refine strategies to enhance vaccine adherence in sickle cell disease.

Cite This Study

Evan Keiser (2025) studied this question.

synapsesocial.com/papers/69362f444fa91c937236d5b9 https://doi.org/10.1182/blood-2025-2596

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Implication

Quality improvement initiatives improved pneumococcal and influenza vaccination rates in adults with sickle cell disease, suggesting better adherence strategies are needed.

Addressing functional asplenia in sickle cell disease: A quality improvement approach to improve vaccination rates

Discussion

Member takes

Implication

Key Points

Cite This Study

Addressing functional asplenia in sickle cell disease: A quality improvement approach to improve vaccination rates

Discussion

Member takes

Implication

Key Points

Cite This Study

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