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December 8, 2025Blood

Real-world patient characteristics, treatment patterns, and outcomes in patients with myelodysplastic syndromes

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SZShiyun ZhuKPKenneth Poon

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Overview

Retrospective cohort analysis highlights erythropoietin-stimulating agents impact on outcomes in myelodysplastic syndromes.

Key Points

  • Transfusion independence rates were higher in untreated patients compared to those receiving erythropoietin-stimulating agents, indicating better baseline health.
  • Among 561 patients, 25.5% had higher-risk myelodysplastic syndromes and transformation to acute myeloid leukemia reached 51.7%.
  • Retrospective cohort analysis from 2019-2024 provides comprehensive data on treatment patterns for myelodysplastic syndromes.
  • Overall survival in lower-risk myelodysplastic syndromes patients receiving treatments varied, showing the direct influence of specific therapies.

Cite This Study

Zhu et al. (2025) studied this question.

synapsesocial.com/papers/69362f3d4fa91c937236d4f6https://doi.org/10.1182/blood-2025-7398
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