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December 8, 2025Blood

Prognostic role of FDG-PET in outcomes of relapsed/refractory large B-cell lymphoma treated with CD3-CD20 directed bispecific antibodies

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Authors

DVDavid VenturaMTMarcel TeichertJSJulia Katharina Scholz

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Overview

Observational analysis revealed significant correlations between FDG-PET parameters and progression-free survival in relapsed large B-cell lymphoma, suggesting effective treatment monitoring.

Key Points

  • Progression-free survival was significantly different between low-risk and high-risk groups based on baseline FDG-PET parameters.
  • The cut-off values for FDG-PET metrics had critical implications for predicting patient outcomes.
  • Standardized uptake values in FDG-PET scans were directly associated with mortality risk for patients undergoing treatment.
  • Metabolic response at first follow-up scans plays an important role in forecasting patient prognosis.

Cite This Study

Ventura et al. (2025) studied this question.

synapsesocial.com/papers/69362f3d4fa91c937236d4echttps://doi.org/10.1182/blood-2025-5518
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