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December 8, 2025BloodOpen Access

Can we perform allogeneic hematopoietic cell transplantation (HCT) safely in patients with limited social supports and substantial psychosocial complexity?

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Retrospective cohort study shows similar overall survival in HCT recipients with limited social support, suggesting safety in these cases.

Overall survival at 12 months was comparable between patients with limited versus high social supports.
Assessment included demographic data and psychosocial risk factors, detailing conditions like treatment nonadherence.
Logistic regression analysis indicated psychosocial complexity modestly impacts survival outcomes, emphasizing clinical significance.
Findings support safe allogeneic HCT in patients with psychosocial complexities, urging re-evaluation of access criteria.

Trad et al. (2025) studied this question.

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Retrospective cohort study shows similar overall survival in HCT recipients with limited social support, suggesting safety in these cases.