What question did this study set out to answer?

This research aims to evaluate the perioperative hemostatic effectiveness and safety of efanesoctocog alfa in adults with Hemophilia A.

December 8, 2025BloodOpen Access

Perioperative use of efanesoctocog alfa in Hemophilia A: A dual-center real-world study

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This research aims to evaluate the perioperative hemostatic effectiveness and safety of efanesoctocog alfa in adults with Hemophilia A.
Retrospective review of surgeries at two Hemophilia Treatment Centers
Inclusion of adults with Hemophilia A who received efanesoctocog alfa preoperatively
Data collected on demographics, surgical outcomes, and bleeding events
Intraoperative hemostasis achieved in all cases under efanesoctocog alfa administration
Postoperative bleeding occurred in 10% of surgeries, all minor and manageable
No thromboembolic events observed, with a low transfusion requirement of 1.7%

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Implication

Dual-center study shows effective surgical hemostasis in adults with Hemophilia A using efanesoctocog alfa, suggesting improved management during surgery.

Cite This Study

Al-Banaa et al. (2025) studied this question.

synapsesocial.com/papers/693624dd4fa91c937236d23d https://doi.org/10.1182/blood-2025-3069

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Implication

Dual-center study shows effective surgical hemostasis in adults with Hemophilia A using efanesoctocog alfa, suggesting improved management during surgery.

Perioperative use of efanesoctocog alfa in Hemophilia A: A dual-center real-world study

Key Points

Discussion

Implication

Cite This Study

Perioperative use of efanesoctocog alfa in Hemophilia A: A dual-center real-world study

Key Points

Discussion

Implication

Cite This Study

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