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December 8, 2025BloodOpen Access

Warm autoimmune hemolytic anemia following epstein-barr virus reactivation: An uncommon clinical association

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Authors

FLFelix Lee

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Overview

Case report reveals warm autoimmune hemolytic anemia linked to EBV reactivation, indicating corticosteroid therapy effectiveness.

Key Points

  • This case explores the rare association between warm autoimmune hemolytic anemia and Epstein-Barr virus reactivation.
  • Case evaluation of a 62-year-old male with abnormal liver and kidney function tests
  • Laboratory assessments including complete blood count, hemolysis markers, and autoimmune testing
  • Serology tests for Epstein-Barr virus reactivation
  • Management with prednisone and red blood cell transfusion
  • Diagnosis of warm autoimmune hemolytic anemia established with positive direct antiglobulin test
  • Significant hemolysis markers included elevated indirect bilirubin and lactate dehydrogenase
  • Patient showed clinical improvement post-corticosteroid treatment and transfusion

Cite This Study

Felix Lee (2025) studied this question.

synapsesocial.com/papers/693624dd4fa91c937236d1b2https://doi.org/10.1182/blood-2025-6448
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