Case report reveals paroxysmal nocturnal hemoglobinuria misidentified as immune thrombocytopenia in an elderly patient, highlighting diagnostic challenges.
Key Points
This case aims to highlight the diagnostic complexities of paroxysmal nocturnal hemoglobinuria amid autoimmune conditions.
Case report of an 82-year-old woman with autoimmune disorders and unresponsive thrombocytopenia.
Evaluation included blood tests, flow cytometry, and bone marrow biopsy to confirm diagnosis.
Treatment involved ravulizumab following vaccinations.
Patient initially misdiagnosed with immune thrombocytopenia; correctly identified with paroxysmal nocturnal hemoglobinuria.
Significant improvement in platelet count and clinical symptoms after treatment with ravulizumab.
Sustained hematologic response at six-month follow-up.