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December 8, 2025BloodOpen Access

Socioeconomic, racial, and hospital-level disparities in inpatient mortality among patients with plasma cell dyscrasias: A 2016-2022 nationwide analysis from the national inpatient sample

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Authors

AFA. Dale FlowersDBDiego Olavarria Bernal

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Overview

Retrospective analysis highlights racial and socioeconomic disparities affecting inpatient mortality in plasma cell dyscrasias.

Key Points

  • This study aims to analyze the impact of socioeconomic and hospital-level factors on inpatient mortality in patients with plasma cell dyscrasias.
  • Conducted a retrospective analysis using the National Inpatient Sample from 2016 to 2022.
  • Included adults with plasma cell dyscrasias identified by ICD-10 codes.
  • Assessed socioeconomic status using ZIP-code–linked income quartiles and Charlson Comorbidity Index.
  • Utilized a multivariable survey-weighted logistic regression model to estimate adjusted odds ratios.
  • Excluded patients with missing data on key variables.
  • Analyzed data from 195,384 patients with an overall mean age of 68 years.
  • Found that patients with Medicaid or lacking insurance had higher odds of mortality compared to those with Medicare.
  • Identified higher mortality odds linked to plasma cell leukemia and relapse of multiple myeloma.
  • Noted that treatment at larger hospitals associated with higher mortality rates compared to smaller hospitals.

Cite This Study

Flowers et al. (2025) studied this question.

synapsesocial.com/papers/693624d44fa91c937236d01ahttps://doi.org/10.1182/blood-2025-8129
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