Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025Methods and ProtocolsOpen Access

Identification and Quantitation of 14C-Labeled Catechol Metabolites in Rat Plasma After Intranasal Instillation of Smoldering Eucalyptus Wood Smoke Extract

View Full Paper
Ask AI
Bookmark
Share

Authors

EUEsther A. UbickYKYong Ho Kim

Discussion

Loading...

Member takes

Overview

This study demonstrates catechol metabolism and exposure assessment in rat plasma after eucalyptus smoke inhalation, highlighting biomarker potential.

Key Points

  • This research aims to identify and quantify catechol metabolites in rat plasma after exposure to eucalyptus wood smoke.
  • Rats were exposed to 14C-labeled catechol via intranasal instillation of eucalyptus wood smoke extract.
  • Plasma samples were collected at 5 minutes and 2 hours post-exposure.
  • Parallel accelerator and molecular mass spectrometry (PAMMS) analyzed the samples.
  • Identified primary catechol-derived metabolites include benzene oxide, catechol-cysteine conjugate, and catechol-glutamine conjugate.
  • The parent compound catechol was not detected in plasma samples.
  • Findings indicate rapid metabolism of catechol upon entering circulation.

Cite This Study

Ubick et al. (2025) studied this question.

synapsesocial.com/papers/693624ba4fa91c937236ca4chttps://doi.org/10.3390/mps8060147
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Mutagenicity and Lung Toxicity of Smoldering vs. Flaming Emissions from Various Biomass Fuels: Implications for Health Effects from Wildland Fires2018 · 297 citations