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December 8, 2025Science ProgressOpen Access

The relationship between epicardial adipose tissue and premature ventricular contractions originating from different areas in the right ventricular outflow tract: A cross-sectional study

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Authors

HYHao YaoJCJian ChenXLXueling Li

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Overview

Cross-sectional data shows increased epicardial adipose tissue in PVCs from the RV outflow tract, indicating its different impact by BMI and sex.

Key Points

  • This study explores the link between epicardial adipose tissue and premature ventricular contractions originating in the right ventricular outflow tract.
  • Retrospective enrollment of PVC patients undergoing catheter ablation.
  • Categorization based on mapping results: RVOT septum and RVOT free wall groups.
  • EAT volume and density quantified using chest CT images.
  • Comparison stratified by sex, age, and body mass index (BMI).
  • 127 PVC patients included: 77 with septal RVOT origin, 50 with free-wall origin.
  • Free wall group had significantly higher EAT volumes than septum group (P = 0.021; P = 0.040).
  • No significant EAT density differences between groups.
  • Larger EAT volumes in females and patients with BMI < 23 in the free wall group.

Cite This Study

Yao et al. (2025) studied this question.

synapsesocial.com/papers/693624ba4fa91c937236ca24https://doi.org/10.1177/00368504251404083
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