What question did this study set out to answer?

To investigate the resting-state functional connectivity in individuals with cannabis use disorder.

December 8, 2025Addiction BiologyOpen Access

The Addiction Neurocircuitry and Resting‐State Functional Connectivity in Cannabis Use Disorder: An fMRI Study

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Authors

HTHannah ThomsonAustralian Catholic University HSHannah SehlAustralian Catholic University VMVictoria ManningEastern Health

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Implication

This fMRI study uncovers altered functional connectivity in individuals with cannabis use disorder, indicating neuroadaptations associated with substance use disorders.

Key Points

To investigate the resting-state functional connectivity in individuals with cannabis use disorder.
Examined resting-state functional connectivity in 65 individuals with moderate-to-severe CUD and 42 controls.
Focused on regions of interest linked to addiction neurocircuitry and related functional responses.
Explored correlations between functional connectivity, cannabis exposure, and associated problems.
CUD group exhibited greater functional connectivity than controls in addiction-related regions.
Increased connectivity observed between the putamen and areas related to disinhibition.
Putamen-occupital connectivity correlated with levels of problematic cannabis use and depression symptoms.

Cite This Study

Thomson et al. (2025) studied this question.

synapsesocial.com/papers/693624984fa91c937236c19b https://doi.org/10.1111/adb.70105

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Implication

This fMRI study uncovers altered functional connectivity in individuals with cannabis use disorder, indicating neuroadaptations associated with substance use disorders.

The Addiction Neurocircuitry and Resting‐State Functional Connectivity in Cannabis Use Disorder: An fMRI Study

Discussion

Member takes

Implication

Key Points

Cite This Study

The Addiction Neurocircuitry and Resting‐State Functional Connectivity in Cannabis Use Disorder: An fMRI Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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