Nucleopalladation shows high yields of valuable N-alkyl indoles with unactivated olefins, suggesting a scalable approach.
A regioselective intermolecular nucleopalladation of indolines with unactivated olefins followed by oxidation is developed to access valuable N-alkyl indoles in high yields. This one-pot protocol features operational simplicity, scalability, and...
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Mahiuddin Baidya (2025) studied this question.