December 6, 2025Molecular BiomedicineOpen Access

Neutrophil Extracellular Traps (NETs) in health and disease

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Authors

YNYueli NiKunming Medical University YYYinfeng YangGuangxi University HBHonggang BaiKunming Medical University

Discussion

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Implication

Review reveals neutrophil extracellular traps' involvement in infectious diseases and autoimmune disorders, suggesting potential for targeted therapies.

Key Points

Neutrophil extracellular traps play a crucial role in managing infections and immune responses, pivotal for health.
Dysregulated NET formation is linked to numerous conditions, including autoimmune disorders and cancer progression.
Analysis based on extensive literature and emerging methods highlights complex roles of NETs in various diseases.
Targeting NETs could lead to novel therapeutic strategies, emphasizing the importance of continued research on these structures.

Cite This Study

Ni et al. (2025) studied this question.

synapsesocial.com/papers/69337cfbb3f947a0a125a4e0 https://doi.org/10.1186/s43556-025-00337-9

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Implication

Review reveals neutrophil extracellular traps' involvement in infectious diseases and autoimmune disorders, suggesting potential for targeted therapies.