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December 6, 2025Scientific ReportsOpen Access

A migrasome-related LncRNA signatures for predicting prognosis and immunotherapeutic response in colorectal cancer

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Authors

JCJinlin CaiJFJia-Xi FeiJWJing Wang

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Overview

Analysis reveals a novel migrasome-related lncRNA risk score in colorectal cancer, indicating potential immunotherapy and survival outcomes.

Key Points

  • Patients stratified by risk score showed significant differences in overall survival outcomes, denoting prognosis impact.
  • Kaplan-Meier survival curves demonstrated distinct survival rates based on the prognostic signature in colorectal cancer.
  • Nomogram development utilized a multimodal predicting model to enhance patient prognostic assessment and therapy response.
  • High-risk colorectal cancer patients exhibited lower immune cell infiltration and heightened resistance to immunotherapy efficacy.

Cite This Study

Cai et al. (2025) studied this question.

synapsesocial.com/papers/69337ce8b3f947a0a125a141https://doi.org/10.1038/s41598-025-29304-8
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