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December 5, 2025InsectsOpen Access

Characterization of Cry4Aa Toxin from Bacillus thuringiensis JW-1 and Its Insecticidal Activity Against Bradysia difformis

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Authors

PXPing XuSQShao-Xuan QuJLJinsheng Lin

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Overview

Characterization of Cry4Aa toxin reveals significant toxicity in B. difformis, implying its potential as a biological control agent.

Key Points

  • Toxicity of purified Cry4Aa confirmed effective against B. difformis larvae, with an LC50 of 2.71 ng/mL.
  • Genomic analysis revealed JW-1 features a unique genome comprising one circular chromosome and seven plasmids.
  • Phylogenetic analysis indicates that the Cry4Aa toxin is part of the distinct Cry4Aa toxin cluster.
  • Biological control strategies leveraging Bacillus thuringiensis may offer environmentally friendly pest management alternatives.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/6932313d8e51979591dceecbhttps://doi.org/10.3390/insects16121228
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