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December 5, 2025Scientific ReportsOpen Access

Co-occurrence of mcr-1 and mcr-3 mobilized colistin resistance genes among carbapenem-resistant Pseudomonas aeruginosa in Iran

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Authors

SHSeyed Masoud Hosseini

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Overview

Analysis of clinical Pseudomonas aeruginosa isolates showed colistin resistance genes mcr-1 and mcr-3 co-occur, indicating rising antimicrobial resistance concerns in Iran.

Key Points

  • Carbapenem-resistant Pseudomonas aeruginosa showed colistin resistance genes in clinical isolates.
  • A total of 14 out of 50 isolates exhibited colistin resistance, representing 28% of the strains.
  • Molecular typing revealed a co-occurrence of mcr-1 and mcr-3, with 8% of the strains harboring mcr-1.
  • Strengthening surveillance and infection control measures is crucial to combat antibiotic resistance.

Cite This Study

Seyed Masoud Hosseini (2025) studied this question.

synapsesocial.com/papers/693231118e51979591dce0c3https://doi.org/10.1038/s41598-025-30491-7
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