December 4, 2025BiomedicinesOpen Access

miRNA-155-3p and miRNA-3196 as Potential Biomarkers in Liquid Biopsies of Non-Small Cell Lung Cancer Patients

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DADaniela Alexandre JPJoana Polido SVSalete Valente

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Implication

Analysis shows miR-155-3p and miR-3196 as potential biomarkers in non-small cell lung cancer, suggesting roles in monitoring treatment response and prognosis.

Key Points

miR-155-3p upregulation correlates with advanced disease and survival in non-small cell lung cancer patients.
ROC analysis yielded area under the curve values of 0.881 for miR-155-3p and 0.784 for miR-3196, indicating diagnostic potential.
The study assessed miRNA expression levels in peripheral blood mononuclear cells using RT–qPCR across 200 subjects, revealing significant associations with treatment response.
Finding optimal thresholds for miR-155-3p and miR-3196 may enhance their prognostic value in non-small cell lung cancer management.

Cite This Study

Alexandre et al. (2025) studied this question.

synapsesocial.com/papers/6930e8dbea1aef094cca3cbb https://doi.org/10.3390/biomedicines13122946

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Implication

Analysis shows miR-155-3p and miR-3196 as potential biomarkers in non-small cell lung cancer, suggesting roles in monitoring treatment response and prognosis.

miRNA-155-3p and miRNA-3196 as Potential Biomarkers in Liquid Biopsies of Non-Small Cell Lung Cancer Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

miRNA-155-3p and miRNA-3196 as Potential Biomarkers in Liquid Biopsies of Non-Small Cell Lung Cancer Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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