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December 4, 2025COVIDOpen Access

Documenting Clinical Outcomes Assessed in Outpatients with COVID-19: A Scoping Review of Randomized Controlled Trials

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Authors

CKChia Siang KowDRDinesh Sangarran RamachandramBCBarbara R. Conway

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Overview

Scoping review identifies key clinical outcomes in outpatient COVID-19 trials, highlighting significant gaps and areas for improvement.

Key Points

  • Hospitalization rates and symptom resolution were key outcomes in outpatient COVID-19 trials, emphasizing the need for intervention.
  • Hydroxychloroquine, fluvoxamine, convalescent plasma, and ivermectin were frequently investigated treatments across trials.
  • Randomized controlled trials from the USA, Iran, and Brazil provided data on clinical outcomes for outpatients with COVID-19.
  • Standardized outcome measures are needed in outpatient COVID-19 trials to improve future study designs.

Cite This Study

Kow et al. (2025) studied this question.

synapsesocial.com/papers/6930e8d7ea1aef094cca3971https://doi.org/10.3390/covid5120199
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