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December 4, 2025Journal of Food Science

Grape Seed Extract NSPCC1 Counteracts Mouse Skin Aging via Modulating MAPK and AMPK Pathways

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Authors

YWYufang WangYZYihan ZhangCTChuyue Tu

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Overview

Grape seed extract NSPCC1 reduces skin aging by improving hydration and antioxidant properties in mice, suggesting a novel skincare intervention.

Key Points

  • Grape seed extract NSPCC1 significantly reduces skin aging effects in a mouse model, restoring hydration and antioxidant levels.
  • Treatment with NSPCC1 improved skin elasticity and mitigated signs of oxidative stress and inflammation after UV exposure.
  • Analysis using RNA sequencing reveals that NSPCC1 modulates MAPK and AMPK signaling pathways involved in skin health.
  • These findings support the potential use of Grape Seed Extract as a proactive skincare solution against aging.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/6930dc78ea1aef094cca21f2https://doi.org/10.1111/1750-3841.70620
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