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This is a Literature Review study.

November 30, 2025PeerJOpen Access

Genomics, population dynamics, immune evasion and resistance determinants foster the competence and global dissemination of Klebsiella pneumoniae

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Literature review reveals immune evasion and antibiotic-resistance genes in Klebsiella pneumoniae, indicating the need for new control measures.

K. pneumoniae shows significant immune evasion mechanisms and a large genome size, enhancing its pathogenicity.
Key findings emphasize the role of antibiotic-resistance genes and virulence genes in K. pneumoniae infection.
Population dynamics analysis reveals clonal group CG 14 and CG 258 as globally disseminated clones.
Strategies for managing MDR K. pneumoniae must consider its resistome and evolving resistance traits.

Aslam et al. (2025) studied this question.

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Literature review reveals immune evasion and antibiotic-resistance genes in Klebsiella pneumoniae, indicating the need for new control measures.