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November 30, 2025Therapeutic Advances in Medical OncologyOpen Access

Treatment response and prediction model of radiotherapy for hepatocellular carcinoma with macrovascular tumor thrombus: a multicenter retrospective study

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Authors

QHQizhen HuangJYJing YangXZXiaohong Zhong

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Overview

Multicenter analysis reveals significant treatment response in hepatocellular carcinoma with portal vein tumor thrombus, suggesting improved outcomes with a nomogram model.

Key Points

  • Objective response rates for radiotherapy were higher in the presence of portal vein tumor thrombus compared to primary tumors.
  • Using logistic regression analysis, independent predictors of treatment response were identified, enhancing model accuracy.
  • A nomogram was developed, showing strong predictive capabilities with an area under the curve of 0.788 in the training cohort.
  • Findings highlight the potential for improved radiotherapy strategies in hepatocellular carcinoma with tumor thrombus.

Cite This Study

Huang et al. (2025) studied this question.

synapsesocial.com/papers/692b9da91d383f2b2a37a4cdhttps://doi.org/10.1177/17588359251392117
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