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November 30, 2025The Open Public Health JournalOpen Access

Global Diphtheria Trends and Regional Disparities: A Narrative Review of the Influence of Vaccine Hesitancy, Surveillance Gaps, and Public Health Interventions

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Authors

AYAli Reza YusefiJKJavad Moslemi KiaRRRasoul Raesi

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Overview

Narrative review reveals high diphtheria incidence linked to vaccine hesitancy in Africa and Southeast Asia, indicating interventions are needed.

Key Points

  • Diphtheria incidence is concerning in Africa and Southeast Asia due to low vaccination coverage.
  • Immunization programs demonstrate success in reducing incidence in Europe and North America, highlighting regional disparities.
  • The analysis includes contributions from WHO, ECDC, and various health organizations from 2000 to 2023.
  • Community engagement is vital for improving vaccination coverage and developing public health interventions.

Cite This Study

Yusefi et al. (2025) studied this question.

synapsesocial.com/papers/692b9da91d383f2b2a37a413https://doi.org/10.2174/0118749445428365251112070830
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diphtheria: A Disease of the Past or a Public Health Threat? Prevention Strategies in the 21st Century2025
  2. 2Public perception and health behaviours related to diphtheria risk in Northern Nigeria2025
  3. 3Immunization equity on the rise: Lessons from World Health Organization’s data on the diphtheria-tetanus-pertussis vaccine coverage in the world’s poorest settings2025
  4. 4Global and national trends in childhood vaccination coverage from 1980 to 2023 with forecasts to 20302025
  5. 5Toxigenic diphtheria rarely detected amid rising cases of nontoxigenic <i>Corynebacterium diphtheriae</i> infections in Ontario, Canada, 2011–20232025