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November 30, 2025Emerging Microbes & InfectionsOpen Access

Epidemiology, Genetic Dynamics, and Transmission of the mcr-1 Gene in China

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Authors

BWBoqian WangZLZhong LiMCMingliang Chen

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Overview

Analysis shows mcr-1 gene prevalence in China, suggesting widespread resistance due to colistin use.

Key Points

  • Colistin use in agriculture has likely facilitated the emergence of mcr-1-positive strains in humans.
  • Epidemiological data reveals mcr-1 gene circulated for over 30 years before its detection in 2015.
  • Genetic analysis provides insights into the transmission dynamics of the mcr-1 gene across bacterial populations.
  • Transmission routes indicate significant risks for the emergence of super-resistant bacteria in healthcare settings.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/692b9da01d383f2b2a37a328https://doi.org/10.1080/22221751.2025.2595798
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