Joint Association of Depression and Sleep Duration With All‐Cause and Cardiovascular Mortality: A Cross‐Sectional Study With Inflammation Mediation Analysis
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Overview
Cross-sectional analysis reveals increased mortality risks linked to depression and sleep duration in adults, suggesting inflammation involvement.
Key Points
Elevated risks of all-cause mortality are linked with depression and short sleep duration, highlighting significant health implications.
Long sleep duration shows an HR of 1.84 for all-cause mortality and HR of 2.28 for cardiovascular mortality, indicating strong associations.
Cox proportional hazards regression method used to assess the relationship between depression, sleep duration, and mortality risks across a large cohort.
C-reactive protein may mediate the connections between joint effects of depression and sleep duration with increased mortality risk.