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November 30, 2025Food FrontiersOpen Access

Peach Kernel Oil Modulates Lipid Metabolism Disorder in ApoEa CRISPR/ Cas9 Gene‐Disrupted Zebrafish

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Implication

Observational analysis shows peach kernel oil reduces lipid accumulation in zebrafish, suggesting its potential against lipid metabolism disorders.

Key Points

  • Lipid metabolism disorder was significantly induced following high-fat diet in ApoEa zebrafish model.
  • Total cholesterol rose noticeably, with increased lipid droplet abundance and vascular accumulation after 5 days.
  • Analysis using zebrafish model indicated that peach kernel oil activates the Jak-STAT signaling pathway by inhibiting stat1b.
  • Findings highlight the potential of peach kernel oil in addressing cardiovascular disease linked to lipid disorders.

Cite This Study

A 2025 study studied this question.

synapsesocial.com/papers/692b9da01d383f2b2a37a22ahttps://doi.org/10.1002/fft2.70156
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