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November 30, 2025BiosensorsOpen Access

Aptamer-Based Gold Nanoparticle Lateral Flow Assay for Rapid Detection of Cardiac Troponin I

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Authors

JZJing ZhangJPJiayi PangCCCheng Cui

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Overview

Aptamer-based assay improves detection of cardiac troponin I in resource-limited settings, indicating high accuracy and stability.

Key Points

  • Detection limit was 11.70 ng·mL−1 for cardiac troponin I, and recovery rates ranged from 95.11% to 103.17%.
  • Assessment using a dual-aptamer sandwich system on a lateral flow assay demonstrated excellent analytical accuracy.
  • Stability was confirmed with test strips remaining effective after four months at room temperature.
  • This method supports timely detection of acute myocardial infarction in point-of-care settings.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/692b94601d383f2b2a37919ehttps://doi.org/10.3390/bios15120776
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