Examining the effect of universal testing and treatment strategies for HIV prevention in Zambia and South Africa: generalizing the results of the HPTN 071 (PopART) trial

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Observational analysis found lower risk of HIV acquisition with weighted estimates in adults, suggesting treatment strategies may improve prevention.

HIV prevention strategies showed a significant reduction in the risk of HIV acquisition with weighted estimates in certain demographics.
In South Africa, risk difference estimates indicated intervention effects with lower HIV rates in treated populations compared to standard of care.
Assessment compared risks of HIV acquisition in adults aged 18-44 using weighted estimates based on demographics and treatment strategies.
This highlights the importance of understanding demographic impacts on HIV prevention efficacy across diverse treatment strategies.

Shook-Sa et al. (2025) studied this question.

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Observational analysis found lower risk of HIV acquisition with weighted estimates in adults, suggesting treatment strategies may improve prevention.