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November 30, 2025International Journal of Gynecological PathologyOpen Access

Mesonephric-like Adenocarcinoma (MLA) Diagnostic Criteria and Controversies: Perspectives and Guidance From Pathologists in the MLA Consortium

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Authors

AMAnne M. MillsEEElizabeth D. EuscherWMW Glenn McCluggage

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Implication

Pathologists provide guidance on diagnostic criteria for gynecologic malignancy, addressing ongoing controversies and improving practices.

Key Points

  • MLA diagnostic criteria remain contentious, highlighting the need for refined guidelines on diagnosis.
  • Key features include immunohistochemical and morphologic similarities to related tumor types in gynecologic malignancy.
  • Pathologists at M.D. Anderson Cancer Center formed a consortium to advance understanding and treatment of MLA.
  • Research collaboration emphasizes the importance of literature review in establishing best practices for MLA diagnosis.

Cite This Study

Mills et al. (2025) studied this question.

synapsesocial.com/papers/692b94261d383f2b2a3783d7https://doi.org/10.1097/pgp.0000000000001150
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