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November 28, 2025Molecular NeurobiologyOpen Access

Linking Mitochondrial Gene Dysregulation to Immune Cell Shifts in Retinitis Pigmentosa

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Mitochondrial dysfunction correlates with immune cell shifts in Retinitis Pigmentosa, highlighting a complex interplay.
Transcriptomic analysis identified 280 mitochondrial-related differentially expressed genes linked to vision decline.
Immunological profiling showed elevated neutrophils and reduced regulatory T cells in Retinitis Pigmentosa pathogenesis.
Understanding these pathways may lead to innovative treatments aimed at halting vision loss.

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Transcriptomic analysis reveals increased neutrophils and mitochondrial dysfunction in Retinitis Pigmentosa, suggesting new therapeutic targets.

Liang et al. (2025) studied this question.

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Transcriptomic analysis reveals increased neutrophils and mitochondrial dysfunction in Retinitis Pigmentosa, suggesting new therapeutic targets.