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November 28, 2025International Journal of Molecular SciencesOpen Access

Identification of a Novel Salivary Four-miRNA Signature for Non-Invasive Diagnosis of Oral Squamous Cell Carcinoma

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Authors

ACAlessia CiringioneGLGiovanni LilloniLTLucas Moron Dalla Tor

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Overview

Analysis reveals a novel four-miRNA signature in OSCC, suggesting non-invasive diagnostic potential for early detection.

Key Points

  • Salivary biomarkers indicate a potential breakthrough for non-invasive OSCC diagnosis.
  • Key findings show specificity of 96.7% and sensitivity of 86.7% for the four-miRNA signature.
  • Reverse transcription was integral to the analysis of miRNA expression in saliva samples.
  • Findings suggest the need for larger studies to confirm the diagnostic value of these biomarkers.

Cite This Study

Ciringione et al. (2025) studied this question.

synapsesocial.com/papers/6928f12ea65b730b9ea7a7b3https://doi.org/10.3390/ijms262311373
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