November 28, 2025BMC GeriatricsOpen Access

Cumulative effect of intrinsic capacity domains on geriatric syndromes and functionality in older inpatients

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Discussion

Retrospective study reveals that declines in cognition and vitality strongly predict functional impairments and frailty in hospitalized older adults.

Cognitive impairment is linked to a nearly six-fold increase in fall risk, emphasizing the need for regular assessment.
Logistic regression models identified significant associations between intrinsic capacity domains and geriatric syndromes.
Almost 60% of older inpatients exhibited moderate to severe declines in intrinsic capacity, particularly in vitality and locomotion.
Routine evaluations of gait speed and psychological well-being may inform targeted interventions for at-risk individuals.

Gencer et al. (2025) studied this question.

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Retrospective study reveals that declines in cognition and vitality strongly predict functional impairments and frailty in hospitalized older adults.