What type of study is this?

This is a Human Clinical Trial study (also classified as: Pre-Registered Trial, RCT).

November 28, 2025NEJM Evidence

Minimally Invasive versus Open Pancreatoduodenectomy for Resectable Neoplasms

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Observational analysis found noninferior overall complications in patients with resectable periampullary neoplasm.

Noninferior overall complications observed following minimally invasive versus open pancreatoduodenectomy.
Patients experienced 90-day overall complications rates similar in both approaches, indicating effective surgical options.
Assessment using clinical data from patients with resectable pancreatic and periampullary neoplasm suggests favorable outcomes.
Findings may guide surgical decisions, although further studies are needed for broader applicability.

Graaf et al. (2025) studied this question.

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