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November 25, 2025Journal of Nutrition and MetabolismOpen Access

Muscle–Bone Relationship: Positive Association Between Appendicular Skeletal Muscle Mass and Bone Microarchitecture in Postmenopausal Women

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Authors

CVCamila Vilarinho VidigalPGPatrícia Paula da Fonseca GriliGCGeise Ferreira da Cruz

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Overview

Cross‐sectional study shows positive association of appendicular skeletal muscle mass and bone microarchitecture in postmenopausal women, indicating muscle health's importance for bone density.

Key Points

  • To investigate associations between sarcopenia components and bone microarchitecture in postmenopausal women.
  • Cross‐sectional study of 98 women aged 50 and above
  • Measured sociodemographic, lifestyle, and clinical characteristics
  • Calculated appendicular skeletal muscle mass index and bone mineral density via dual energy X‐ray absorptiometry
  • Evaluated bone microarchitecture using trabecular bone score
  • Analyzed associations using multivariate linear regression with adjusted models.
  • ASMI positively associated with bone microarchitecture after model adjustment (β = 0.047; p = 0.015)
  • Participants were mostly aged 60-69.9 years
  • High percentage did not smoke (94.9%) or consume alcohol (87.8%).

Cite This Study

Vidigal et al. (2025) studied this question.

synapsesocial.com/papers/692502ad87af00ed34ac1c40https://doi.org/10.1155/jnme/3170619
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