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August 25, 2023New England Journal of Medicine1,578 citationsOpen Access

Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity

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MKMikhail KosiborodSASteen Z. AbildstrømBBBarry A. Borlaug

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Abstract

In patients with heart failure with preserved ejection fraction and obesity, treatment with semaglutide (2.4 mg) led to larger reductions in symptoms and physical limitations, greater improvements in exercise function, and greater weight loss than placebo. (Funded by Novo Nordisk; STEP-HFpEF ClinicalTrials.gov number, NCT04788511.).

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Kosiborod et al. (2023) studied this question.

synapsesocial.com/papers/690bcb9affaa946ed682a03bhttps://doi.org/10.1056/nejmoa2306963
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Also Consider

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  1. 1Weight change and the conservation of lean mass in old age: the Health, Aging and Body Composition Study2005 · 444 citations
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