Two cases of sex cord–like endometrioid carcinoma demonstrate variability in histology and immunophenotype, suggesting enhanced diagnostic evaluation is needed.
Key Points
A thorough immunohistochemical evaluation revealed key markers including CDX-2 and PAX-8 across both cases.
Diagnostic imaging initially suggested fibroid diagnosis in both patients, indicating possible misinterpretation of symptoms.
Histologic evaluation disclosed a sex cord–like pattern, underscoring the complexity of diagnosing this rare carcinoma subtype.
The presence of abdominal pain was common in both patients, illustrating a shared presenting symptom for SCLEC.