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October 27, 2025BiomoleculesOpen Access

Molecular Pathogenesis of Arrhythmogenic Cardiomyopathy: Mechanisms and Therapeutic Perspectives

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Molecular pathogenesis underscores the link between genetic mutations and ventricular arrhythmias.
A key concern is the high risk of sudden cardiac death associated with arrhythmogenic cardiomyopathy.
Current therapeutic strategies like catheter ablation offer palliative care but do not target underlying molecular mechanisms.
Animal models, particularly murine, enhance understanding of myocardial remodeling in arrhythmogenic cardiomyopathy.

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Review highlights genetic mutations and emerging therapies in arrhythmogenic cardiomyopathy, suggesting improved disease management strategies.

Popa et al. (2025) studied this question.

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Review highlights genetic mutations and emerging therapies in arrhythmogenic cardiomyopathy, suggesting improved disease management strategies.