Investigation shows agreement in susceptibility testing methods for ceftibuten and avibactam against Enterobacterales, indicating effectiveness against resistant strains.
Key Points
High correlation in susceptibility testing methods for ceftibuten and avibactam ensures reliable treatment options.
Essential agreement of 90% or more was observed across broth and agar dilution methods on 153 isolates.
Broth microdilution testing was largely unaffected by varying parameters, enhancing reliability for the combination therapy.
The findings highlight the need for oral therapeutic options against antibiotic-resistant bacteria in clinical settings.