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October 23, 2025Open Access

Relations between retinal microvasculature by optical coherence tomography angiography and cerebral small vessel disease in individuals with type 1 diabetes

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Authors

ATAleksi TarkkonenIKIiris KyläheikoMEMarika I. Eriksson

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Overview

Observational analysis shows lower vessel densities in individuals with type 1 diabetes and cerebral microbleeds, indicating OCTA may aid cerebrovascular risk stratification.

Key Points

  • Lower retinal vessel densities relate to cerebral microbleeds in individuals with type 1 diabetes, highlighting potential diagnostic value of OCTA.
  • Individuals with type 1 diabetes exhibited lower SCP and DCP vessel densities compared to healthy controls with significant associations noted for age and diabetes duration.
  • Assessment using optical coherence tomography angiography and brain MRI identified key microvascular changes related to cerebrovascular health.
  • These findings suggest OCTA may assist in cerebrovascular risk stratification but does not predict white matter hyperintensities.

Cite This Study

Tarkkonen et al. (2025) studied this question.

synapsesocial.com/papers/68f9bad7d7353cfcfc68f608https://doi.org/10.1101/2025.10.20.25338353
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Early detection of retinal changes in children with diabetes without retinopathy using optical coherence tomography and optical coherence tomography angiography2025
  2. 2Optic Disc and Macular Vessel Density Measured by Optical Coherence Tomography-Angiography in Diabetic Patients2024 · 1 citations
  3. 3Choroidal vascular alterations in diabetic retinopathy and their association with macular microvascular parameters2025 · 4 citations
  4. 4Longitudinal Changes in Anatomic Biomarkers on Optical Coherence Tomography Angiography in Diabetic Retinopathy2025
  5. 5Assessment of early macular and peripapillary diabetic vascular changes using optical coherence tomography angiography2025