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October 23, 2025Open Access

Associations Between the CHG Index, Its Modified Versions, and Incident Stroke in Early-Stage CKM Syndrome: A Nationwide Cohort Study

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Nationwide cohort study demonstrates CHG index predicts incident stroke in CKM syndrome, suggesting enhanced stroke prevention strategies.

Incident stroke risk increases with rising cholesterol and insulin resistance among CKM syndrome patients.
Over a 9-year follow-up, 575 stroke cases highlighted key associations with the CHG index and its variants.
Prospective cohort study utilized multivariable Cox models to evaluate cardiovascular outcomes in CKM syndrome.
Findings indicate that early detection through the CHG index could improve stroke prevention efforts in vulnerable populations.

Ke et al. (2025) studied this question.

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Nationwide cohort study demonstrates CHG index predicts incident stroke in CKM syndrome, suggesting enhanced stroke prevention strategies.