In vitro analysis shows that optimized curcumin-piperine magnetic nanoparticles reduce cell viability in colorectal cancer, suggesting improved drug delivery.
Key Points
Optimized curcumin-piperine magnetic nanoparticles reduced cell viability in colorectal cancer cells.
The IC50 of the nanoparticles indicates strong cytotoxicity with a particle size averaging 158.7 nm.
Assessment using cytotoxicity assays and confocal microscopy revealed a synergistic effect in HCT-116 cells.
These findings highlight the potential of targeted drug delivery using phytoconstituents for cancer therapy.