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October 23, 2025Saudi Journal of MedicineOpen Access

Fatal Wernicke’s Encephalopathy Following Severe Acute Pancreatitis: A Rare Case Report

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Authors

SJSidi Driss El JaouhariZHZakaria El HamdaniYHYoussef Hnach

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Overview

Case report highlights mortality due to Wernicke’s encephalopathy in a patient with severe acute pancreatitis, suggesting early thiamine supplementation may improve outcomes.

Key Points

  • Mortality was observed in a patient with Wernicke’s encephalopathy and severe acute pancreatitis, indicating significant risk.
  • A 54-year-old woman presented with confusion and ocular abnormalities following multiorgan failure and nutritional deficiencies.
  • Neuroimaging confirmed Wernicke’s encephalopathy diagnosis in this critical care case, underscoring diagnostic challenges.
  • Early thiamine supplementation may prevent fatal outcomes in patients at risk for nutritional deficiencies.

Cite This Study

Jaouhari et al. (2025) studied this question.

synapsesocial.com/papers/68f9a0eb8ea8f2f37ee94b40https://doi.org/10.36348/sjm.2025.v10i10.003
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Wernicke’s Encephalopathy Complicated by Postoperative Digestive Fistula and Severe Nutritional Deficits2025
  2. 2Wernicke encephalopathy: a mini review of the clinical spectrum, atypical manifestations, and diagnostic challenges.2025
  3. 3Wernicke’s encephalopathy associated with alcoholism and precipitated by intravenous glucose2025
  4. 4Wernicke-Korsakoff syndrome in the emergency department: a case report2025
  5. 5Dynamic progression of Wernicke encephalopathy in a gastric cancer patient: Multimodal MRI insights with arterial spin labeling perfusion imaging.2025