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October 23, 2025Advanced Functional Materials

Se Polyurethane‐Coated Titanium for Improved Osteogenesis and Immune Response

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Authors

MZMo ZhaiStomatology Hospital BXBanruo XianyuTsinghua University HZHonglin ZhangJilin University

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Implication

Selenium-containing polyurethane promotes osteogenic differentiation and reduces inflammation in diabetic and osteoporotic models, indicating better titanium implant performance.

Key Points

SePU improved osteogenesis in diabetic and osteoporotic rats, enhancing overall implant integration.
M2 polarization of macrophages was induced, resulting in decreased inflammation and better healing.
RNA-sequencing showed regulation of NRF2-mediated oxidative stress, reducing oxidative damage and supporting tissue repair.
These findings highlight the potential of selenium in addressing challenges faced by titanium implants in compromised systems.

Cite This Study

Zhai et al. (2025) studied this question.

synapsesocial.com/papers/68f9a0eb8ea8f2f37ee94b18 https://doi.org/10.1002/adfm.202514534

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Implication

Selenium-containing polyurethane promotes osteogenic differentiation and reduces inflammation in diabetic and osteoporotic models, indicating better titanium implant performance.

Se Polyurethane‐Coated Titanium for Improved Osteogenesis and Immune Response

Discussion

Member takes

Implication

Key Points

Cite This Study

Se Polyurethane‐Coated Titanium for Improved Osteogenesis and Immune Response

Discussion

Member takes

Implication

Key Points

Cite This Study

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